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Advanced Therapies

Some patients who suffer recurrent infections or viral symptoms may benefit from transfer factor or isoprinosine, which are thought to reduce viral load and possibly moduate the immune system. When gamma globlin or IgG subclasses are low, intravenous or subcutaneous gamma globulin has been helpful

The research literature supports the use of growth hormone and low dose cortisol in many people with CFS/FM whose hypothalamic-pituitary –adrenal axis (HPA axis) is suppressed by their illness. That is, the hypothalamus, pituitary, adrenals, and other glands (such as the thyroid and sex glands) function poorly.  

The poor functioning would be evidenced by low levels of DHEA-S, IGF1 (a measure of growth hormone), estrogen (in females), testosterone (in males), morning cortisol or 24-hour urinary cortisol production. In such cases, the use of hormones and steroids may provide modest benefit.

Lastly, Ampligen is an immune modulator that has been under study since 1988 for the treatment of Chronic Fatigue Syndrome. The manufacturer, AIM Immunotech, is currently seeking FDA approval for the use of this drug in CFS. It is an investigatioal drug only available at the the Hunter-Hopkins Center (Charlotte NC) and Dr. Dan Peterson’s clinic, (Lake Tahoe NV) as part of an experimental protocol.